Ibicuruzwa
Inzobere mu gukora inzoga za propargyl, 1,4 butynediol na 3-chloropropyne
Inzira yo gukora inzoga ya propargyl no gusesengura isoko
Ibyiza nibisabwa bya alcool 2 ya propargyl
2.1 Igikorwa cyiza cyo hejuru no gutatanya
Inzoga ya Propargyl ifite polarite ikomeye na hydrophilicity, kubera ko irimo -OH, na hydrophobicity ni ukubera ko irimo itsinda rya hydrocarubone, kubera ko iyi mitungo ituma inzoga ya propargyl itagaragara nka ionic surfactant, yerekana imikorere myiza, hamwe no kubira ifuro rito, kwangiza no gutose.Ibikoresho byinshi byo guhanagura byoroshye, mugihe imiti myinshi yangiza imiti ifite ububobere buke.Ugereranije nizindi surfactants, alkyl alcool ifite uburemere buke bwa molekile, gukwirakwira byoroshye, gutatanya neza, guhindagurika neza hamwe nifuro nke.Ku ruhande rumwe, alcool ya alkyl irimo hydrocarubone ishingiye kumashami yiminyururu, cyane cyane matsinda mato (muri rusange methyl), hariho amatsinda abiri ya polar muburyo.Kubera iyi miterere yimiti, alkyl alcool ifite wettability nziza.Ku rundi ruhande, iminyururu ya shami ya alkyl muri alcool ya propargyl irashobora kugabanya gukurura hagati ya molekile zituranye kandi igakora firime yo kwaguka kandi ihumeka ku mbibi za gaze-amazi.Kubwibyo, ntabwo ikora ifuro ubwayo, ahubwo ifite n'ubushobozi bumwe bwo gusebanya, kandi irashobora kuvangwa nibindi bikoresho byo gusebanya kugirango bigire uruhare runini.
2.2 Kubuza icyuma cyiza cyane
Kugeza ubu, ibyuma byangiza ruswa ikoreshwa mu bitangazamakuru bya acide ahanini ni ibinyabuzima kama, bifite ubushobozi bwa adsorption bukomeye hejuru yicyuma.Imiterere ya molekulire yinzoga ya propargyl ikubiyemo amatsinda ya polar hamwe nitsinda ridafite inkingi.Ni adsorbent ya organic positif inhibitor.Ku ruhande rumwe, guhuza ibikorwa byakozwe hagati yinzoga ya propargyl na atome yicyuma biteza imbere kwinjiza inzoga kurwego runaka.Muri icyo gihe, isano ya PI muri molekile ya alcool ya propargyl iracika intege, isano ya gatatu irakora, kandi itsinda rya hydroxyl polar ryegereye umurunga wa acetylene, wongera adsorption.Muburyo bwa alkaline, inzoga ya proparynyl irashobora adsorb Langmuir kuri aluminiyumu nziza, ifite ingaruka nziza zo kubuza ruswa.Inzoga ya Propargyl ni ukubera imikorere yayo myiza, ifite uburyo bwinshi bwo gukoresha, ikoreshwa cyane cyane mubunzi ba farumasi, umuringa cyangwa nikel isahani ya poli, imiti yica udukoko.Byongeye kandi, inzoga ya propargyl irashobora kandi gukoreshwa nkikumira ryangirika ryubushyuhe bwo hejuru, umuvuduko mwinshi hamwe na aside hydrochloric yibanda cyane mumavuta na gaze gasanzwe Wells.
2.3 Gukoresha inzoga ya propargyl
Abahuza b'ingenzi muri synthesis organique: mu nganda zimiti, proparynol ni intera ikomeye ya sodium fosfomycine, calcium fosfomycine, sulfadiazine, kandi ikoreshwa no mu gukora inzoga za allyl, acrylic, vitamine A nibindi bicuruzwa bivura imiti;Inganda zikoresha amashanyarazi: ibinyobwa bisindisha bya propargyl bifite uburinganire bwiza nuburabyo, hamwe no kurwanya urumuri rwiza mu isahani ya nikel.Nibisanzwe igisekuru cya kane nikel isahani yamurika, ikoreshwa cyane mumashanyarazi;Rem Gukuraho ingese zingenzi: inzoga ya proparynyl hamwe n’ibicuruzwa byayo byo hepfo birashobora kubuza kwangirika kwicyuma, umuringa, nikel nibindi byuma ukoresheje aside nka acide acike, aside fosifori, aside sulfurike, aside hydrochloric;.⑤ irashobora gukoreshwa nka solvent, chlorine hydrocarbon stabilisateur, fungiside nibindi bikoresho fatizo.
Inzira yumusaruro
Kugeza ubu, uburyo bukoreshwa cyane mu gutegura inzoga za propargyl mu gihugu no hanze yacyo ni reaction ya formaldehyde na acetylene kugirango itange inzoga ya propargyl na butynediol, inzoga ya propargyl ikomoka kuri butynediol.Muguhindura uburyo bwiza bwo gufata gaze ya acetylene, kunoza umuvuduko wa reaction, kumenya agaciro keza pH, igipimo cya alcool ya propargyl na butynediol gishobora kugera kuri 1: 1.6, kugirango tunoze guhitamo inzoga za propargyl.Inzira: Ongeramo umuringa wa ogisijeni wa catisale mu kigega cyo gukora, ongeramo amazi yoroshye, koga nka 20min, hanyuma usukemo imvange ya catalizator n’amazi mu kigega gikurura pompe.Amazi yoroshye hamwe na fordehide yongewemo mukigega cyateguwe kugirango hategurwe igisubizo kivanze kirimo 6% ~ 10% ya fordehide.Amazi akurura yashizwe mumashanyarazi hamwe na pompe yo kugaburira plunger ukurikije igipimo cyapimwe, hanyuma compressor ya acetylene itangira guhindura umuvuduko wa acetylene no kugenzura umuvuduko wa reaction.Sisitemu yubushyuhe bwikora hamwe nigenzura ryumuvuduko wa reaktor yatangiye kugenzura ubushyuhe bwa reaction kuri 90 ~ 130 ℃ numuvuduko kuri (2.0 ± 0.1) MPa.Sisitemu ya reaction irazenguruka nyuma yo gusohoka, hanyuma gusohora bigasubira muri tank.Ibiri muri formaldehyde mubikoresho byagaragaye nyuma ya 0.5h.Iyo formaldehyde isigaye yari munsi ya 0.3%, uruziga rwarahagaritswe hanyuma igisubizo cya reaction gishyirwa mumatara hagati hamwe na propargyl na butanediol biri hafi 4% na 6%.Umusemburo mubikorwa byo kubyaza umusaruro ugomba gusimburwa buri gihe, kandi igihe cyo gusimburwa ni iminsi 30 kugeza 40.Azote ikoreshwa ifatanije na catalizator kugirango ikure ibintu muri sisitemu mugihe cyo kuyisimbuza.Nyuma yo gutandukana nayunguruzo rwumuvuduko, catisale isigaye ishyirwa mububiko bwakoreshejwe bwa catalizator hanyuma igashyirwaho amazi.Cataliseri nshya yanditswe inyuma mubizakurikiraho bya sisitemu yo gutunganya.
Isesengura ryinzoga ya Propargyl
Dezhou Tianyu Chemical Co., Ltd. ni umwe mu musaruro muke wo mu gihugu w’inzoga nini za propargyl na butanediol, umusaruro w’umwaka wa alcool ya propargyl 1200T, butanediol 2400T, hamwe n’ubuziranenge bw’Ubudage BASF bihwanye.Henan Haiyuan Fine Chemical Co., Ltd. yazamuye kandi anonosora umushinga hashingiwe ku buryo bwo gutunganya umusaruro wa mbere wa Shandong Dongfang Le, buri mwaka hasohoka 1200T inzoga za propionyl na 2400T butanediol.Mu Bushinwa, inzoga ya proparynyl ikoreshwa cyane cyane mu guhuza ibiyobyabwenge, sodium fosifate, calcium fosifate, sulfonamide n’imiti yica udukoko, bingana na 60%.Isahani yihuta ya nikel hamwe na flash plaque bingana na 17%.Umusaruro wa peteroli ni 10%;Umugabane wibyuma ni 8 ku ijana;Izindi nganda zingana na 5%.Inzoga ya Propargyl ni imiti ifite ubumara bukabije yumva umusaruro, kwamamaza no gukoresha.Nubuvuzi bwo hepfo, imiti yica udukoko, itangazamakuru ryitwa metallurgical nizindi nzego zabafasha cyangwa kimwe mubigize.Kugeza mu mpera za 2017, umusaruro w’imbere mu gihugu wari 4.770T / a, naho icyifuzo cyari hafi 4.948T / a.Isoko nibisabwa biringaniza, hamwe rimwe na rimwe kubura.
Umwanzuro
Kugeza ubu, irushanwa ry’isoko rya propanol mu gihugu rirakaze, aho rikoreshwa cyane ni uruganda rukora imiti fosfomycine y’uruganda rwa farumasi, hamwe n’ubugenzuzi bw’imikoreshereze mibi ya antibiotike y’igihugu ndetse n’inganda zikoresha amashanyarazi mu bikorwa byo kurengera ibidukikije, abakoresha propanol mu gihe gito mu gihe gito ntabwo bariyongereye.Kugeza ubu, turagerageza kurushaho kunoza uburyo bushya bwo kubyitwaramo, guhora tunoza umusaruro w’inzoga za propargyl, kandi duharanira kugabanya ingufu zikoreshwa n’ibicuruzwa bya alcool.Ishyirwa mu bikorwa ry’iyi mirimo rizakomeza kugabanya igiciro cy’ibicuruzwa by’inzoga za propargyl, bizamura irushanwa ry’ibicuruzwa, kandi bihatire guhaza isoko ry’imbere mu gihugu ndetse n’amahanga ku nzoga za propargyl hamwe n’ibicuruzwa, kugira ngo habeho inyungu nyinshi mu bukungu n’imibereho.
